Looks like pipewire-0.3.81-1 has some issues. At first it looked like it only impacted virtual machines but my laptop turned out to be a victim also. It fails 100% for me in VirtualBox across a wide range of hosts for all current Fedora guests (F37, 38, 39 and Rawhide).
https://bugzilla.redhat.com/show_bug.cgi?id=2242080
For me, last known working version is pipewire-0.3.80-1. Downgrading to this fixes all cases (VMs and native).
All of that said, it's working on 2 other native hosts, however the VMs on those host all fail until Downgrading to 0.3.80-1.
Ian -- Ian Laurie FAS: nixuser | IRC: nixuser TZ: Australia/Sydney